After providing all the funding for The Brain from Top to Bottom for over 10 years, the CIHR Institute of Neurosciences, Mental Health and Addiction informed us that because of budget cuts, they were going to be forced to stop sponsoring us as of March 31st, 2013.

We have approached a number of organizations, all of which have recognized the value of our work. But we have not managed to find the funding we need. We must therefore ask our readers for donations so that we can continue updating and adding new content to The Brain from Top to Bottom web site and blog.

Please, rest assured that we are doing our utmost to continue our mission of providing the general public with the best possible information about the brain and neuroscience in the original spirit of the Internet: the desire to share information free of charge and with no adverstising.

Whether your support is moral, financial, or both, thank you from the bottom of our hearts!

Bruno Dubuc, Patrick Robert, Denis Paquet, and Al Daigen




Monday, 23 July 2012
Alzheimer’s Type Dementia

ficelle-doigtTwo months ago, some new content to The Brain from Top to Bottom has been added: a sub-topic entitled “Alzheimer’s Type Dementia” under the main topic “Mental Disorders”. This form of dementia, more commonly referred to as Alzheimer’s disease, receives a lot of attention in the media, but its causes remain uncertain.

Yes, researchers have discovered biological markers for Alzheimer’s, such as amyloid plaques and neurofibrillary tangles. But the types of cognitive deterioration associated with Alzheimer’s do not always correlate very closely with the presence or absence of such markers. The extent of the loss of synapses is the only physical marker that seems to correlate with the loss of memory and other faculties. But such an analysis is still far from establishing the possible causes of this condition. Moreover, the loss of neurons that occurs naturally in the course of normal aging adds fuel to the vigorous debate about whether Alzheimer’s is actually a disease at all.

But one thing is certain: despite their loss of independence, life goes on for many years for people with Alzheimer’s and for their families. Family members have to cope with changes that often place very heavy demands on them, which is why it is so important to have a good understanding of the family member who has Alzheimer’s and the many abilities that he or she still retains.

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