After providing all the funding for The Brain from Top to Bottom for over 10 years, the CIHR Institute of Neurosciences, Mental Health and Addiction informed us that because of budget cuts, they were going to be forced to stop sponsoring us as of March 31st, 2013.

We have approached a number of organizations, all of which have recognized the value of our work. But we have not managed to find the funding we need. We must therefore ask our readers for donations so that we can continue updating and adding new content to The Brain from Top to Bottom web site and blog.

Please, rest assured that we are doing our utmost to continue our mission of providing the general public with the best possible information about the brain and neuroscience in the original spirit of the Internet: the desire to share information free of charge and with no adverstising.

Whether your support is moral, financial, or both, thank you from the bottom of our hearts!

Bruno Dubuc, Patrick Robert, Denis Paquet, and Al Daigen




Monday, 25 March 2013
Donating Your Brain to Science

People who donate their brains to be used in neuroscientific research after they die are making a great contribution to our understanding of normal aging and of aging-related disorders such as Alzheimer’s disease. Normally, such donations are made anonymously, but for the sake of an exhibition designed to draw attention to this humanitarian gesture, 12 brain donors aged 84 to 100 gave the organizers permission to disclose their identities. (more…)

Mental Disorders | No comments


Tuesday, 19 March 2013
The “God” of Apple and His Disciples

When Steve Jobs died, fans paid tribute by laying flowers and apples alongside burning candles at impromptu shrines around the world. One fan crafted the modified Apple logo shown here, with Jobs’s silhouette resembling what some Christians believe to the image of Jesus on the Shroud of Turin, a famous religious relic.

This analogy with religion may seem a bit forced, but not according to a study reported on the BBC documentary series Secrets of the Superbrands, which examines the cult-like devotion that some people display for major brands such as Apple. In this study, British neuroscientists tried to determine whether this analogy might be more than superficial. They were especially curious to see which parts of an Apple fan’s brain altered their activity when he was shown pictures of Apple products. (more…)

The Emergence of Consciousness | No comments


Monday, 11 March 2013
Free Radicals and Aging: More Complicated Than We Thought

In 2010, Dr. Siegfried Hekimi and his colleagues at McGill University in Montreal received a great deal of media coverage for their research showing that antioxidants, which many people take as food supplements to fight the damaging effects of free radicals, not only do not slow down the aging process but on the contrary might actually accelerate it. Even more unbelievably, when the researchers used Caenorhabditis elegans, a species of small worms, as an animal model and exposed them to an herbicide that is toxic to humans and generates a lot of free radicals, these worms lived 60% longer than worms who were not exposed to it! (more…)

Mental Disorders | 1 comment


Monday, 4 March 2013
Remembering Every Day of Your Life

Thanks to your episodic memory, you can easily remember what you ate yesterday or what you did last weekend. But if you try to go back a few weeks or months, or especially a few years, you’ll see that you’ve lost most of your autobiographical memories, except possibly for a few events with a strong emotional impact. Instead, your semantic memory will have taken over, generalizing from the recurrent features of your life to develop abstract concepts—and that is as it should be.

But a very small number of people (about 20 have been identified to date) have highly superior episodic memories that let them recall what they did on virtually any specific day in their lives, 10, 20, or even 30 years later! (more…)

Memory and the Brain | No comments