After providing all the funding for The Brain from Top to Bottom for over 10 years, the CIHR Institute of Neurosciences, Mental Health and Addiction informed us that because of budget cuts, they were going to be forced to stop sponsoring us as of March 31st, 2013.

We have approached a number of organizations, all of which have recognized the value of our work. But we have not managed to find the funding we need. We must therefore ask our readers for donations so that we can continue updating and adding new content to The Brain from Top to Bottom web site and blog.

Please, rest assured that we are doing our utmost to continue our mission of providing the general public with the best possible information about the brain and neuroscience in the original spirit of the Internet: the desire to share information free of charge and with no adverstising.

Whether your support is moral, financial, or both, thank you from the bottom of our hearts!

Bruno Dubuc, Patrick Robert, Denis Paquet, and Al Daigen

Monday, 22 August 2016
A good general book on neuroscience

Whenever I give a presentation about the human brain, someone almost always comes up afterward and asks me whether I could recommend a good general book on neuroscience. In fact, there are several such books, but the one that I want to recommend here today offers a special advantage: you can buy a printed copy, but you can also access the entire book on the Internet for free!

The book that I’m talking about is Neuroscience, 2nd edition, edited by Dale Purves et al. and published by Sinauer Associates in 2001. It covers wide areas of modern neuroscience and is chock-full of very informative figures and tables. (more…)

From the Simple to the Complex | No comments

Monday, 8 August 2016
A Nanometric 3D Representation of a Mouse Cortex Cortex

The analogy between a real forest and a “forest of neurons” has been drawn many times, but the images produced most recently by the team of Jeff Lichtman and Narayanan Kasthuri (see the first two links below) make it clear yet again that the complexity of the brain’s connections far surpasses that of the densest forest.

As Lichtman has long said, by going down to the scale of the electron microscope and then reconstructing the slightest contacts between axons, dendrites, and neighbouring glial cells slice by slice, we can detect patterns that escape us at the more “macro” scales previously used to model neuronal connectivity. (more…)

From the Simple to the Complex | No comments