After providing all the funding for The Brain from Top to Bottom for over 10 years, the CIHR Institute of Neurosciences, Mental Health and Addiction informed us that because of budget cuts, they were going to be forced to stop sponsoring us as of March 31st, 2013.

We have approached a number of organizations, all of which have recognized the value of our work. But we have not managed to find the funding we need. We must therefore ask our readers for donations so that we can continue updating and adding new content to The Brain from Top to Bottom web site and blog.

Please, rest assured that we are doing our utmost to continue our mission of providing the general public with the best possible information about the brain and neuroscience in the original spirit of the Internet: the desire to share information free of charge and with no adverstising.

Whether your support is moral, financial, or both, thank you from the bottom of our hearts!

Bruno Dubuc, Patrick Robert, Denis Paquet, and Al Daigen




Monday, 25 February 2013
Links on Pleasure-Seeking Behaviour

This week, as I have before in this blog,  I am posting a set of new links to other web sites that discuss a subject covered in The Brain from Top to Bottom. The subject this week is the sub-topic “Pleasure-Seeking Behaviour”, under the topic “Pleasure and Pain”. For each link, I also provide a brief description of the content on the site in question. (more…)

Pleasure and Pain | Comments Closed


Monday, 18 February 2013
4 New RSS Feeds for Recent News About the Brain

As you may have noticed, last week we added a new feature to The Brain from Top to Bottom Blog to help you follow the latest news in the vast field of neuroscience. I’m talking about the four RSS feeds now appearing in the left-hand column under the heading “RECENT NEWS ABOUT THE BRAIN”. (more…)

From the Simple to the Complex | Comments Closed


Monday, 11 February 2013
Neurons with Surprising Properties

Just when scientists thought they had a pretty good understanding of how neurons communicate, along comes a new set of seemingly abnormal data that overturn the official paradigm (such upheavals are not uncommon in the world of science). Any good neuroscience textbook will tell you that neurons are stimulated or inhibited by input signals that they receive through the synapses between their dendrites or cell bodies and other neurons. As a neuron receives all these signals, it integrates them, and then fires one or more action potentials into its axon. These action potentials travel down to the tip of the axon, where they cross synapses to other neurons, and so on.

But as a team of researchers from Northwestern University, in Illinois in the United States, discovered and reported in the February 2011 issue of Nature Neuroscience, the process just described is clearly not the only way that nerve impulses travel through neurons. (more…)

From the Simple to the Complex | Comments Closed


Monday, 4 February 2013
Adelson’s Checkerboard

Optical illusions are always a humbling experience for people who think that they see the world “the way it really is”. Often, when such people are confronted with optical illusions induced by context, the context has to be removed and then restored several times before these people can be convinced that, for example, two lines that appear to be different lengths are actually the same.

The world that we see is often ambiguous, and our visual system tries to give it a meaning on the basis of certain recurrent clues. Scientists today are familiar with some of these clues and can combine them to produce some truly astounding optical illusions. One famous example is Adelson’s checkerboard, in which one square is perceived as black and another as white, even though both are actually the same shade of grey! (more…)

The Senses | Comments Closed