Monday, 8 August 2016
A Nanometric 3D Representation of a Mouse Cortex Cortex
The analogy between a real forest and a “forest of neurons” has been drawn many times, but the images produced most recently by the team of Jeff Lichtman and Narayanan Kasthuri (see the first two links below) make it clear yet again that the complexity of the brain’s connections far surpasses that of the densest forest.
As Lichtman has long said, by going down to the scale of the electron microscope and then reconstructing the slightest contacts between axons, dendrites, and neighbouring glial cells slice by slice, we can detect patterns that escape us at the more “macro” scales previously used to model neuronal connectivity. (more…)
From the Simple to the Complex | No comments
Monday, 14 October 2013
Axons Play Unexpected Role in Processing Information
Recently, someone asked me whether it would be fair to say that the integration of all the information that one neuron receives from other neurons takes place in its dendrites. I replied that according to the classic model of neural communication, that is certainly the case, but that processes in living organisms are highly complex, so I probably shouldn’t make that statement categorically, if only because some integration also occurs directly in the neuron’s cell body. (more…)
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