After providing all the funding for The Brain from Top to Bottom for over 10 years, the CIHR Institute of Neurosciences, Mental Health and Addiction informed us that because of budget cuts, they were going to be forced to stop sponsoring us as of March 31st, 2013.

We have approached a number of organizations, all of which have recognized the value of our work. But we have not managed to find the funding we need. We must therefore ask our readers for donations so that we can continue updating and adding new content to The Brain from Top to Bottom web site and blog.

Please, rest assured that we are doing our utmost to continue our mission of providing the general public with the best possible information about the brain and neuroscience in the original spirit of the Internet: the desire to share information free of charge and with no adverstising.

Whether your support is moral, financial, or both, thank you from the bottom of our hearts!

Bruno Dubuc, Patrick Robert, Denis Paquet, and Al Daigen





Monday, 6 July 2020
Acute stress reaction initiated by a hormone secreted by the bones

Today I’d like to tell you about an article published in the journal Cell Metabolism in September 2019. The article, entitled “Mediation of the Acute Stress Response by the Skeleton”, reports a discovery that is surprising, to say the least. Apparently, all on its own and in just a few minutes, osteocalcin, a hormone produced in our bones, can initiate the physiological changes associated with acute stress, such as increased heart rate, respiratory rate and blood pressure. (more…)

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