After providing all the funding for The Brain from Top to Bottom for over 10 years, the CIHR Institute of Neurosciences, Mental Health and Addiction informed us that because of budget cuts, they were going to be forced to stop sponsoring us as of March 31st, 2013.

We have approached a number of organizations, all of which have recognized the value of our work. But we have not managed to find the funding we need. We must therefore ask our readers for donations so that we can continue updating and adding new content to The Brain from Top to Bottom web site and blog.

Please, rest assured that we are doing our utmost to continue our mission of providing the general public with the best possible information about the brain and neuroscience in the original spirit of the Internet: the desire to share information free of charge and with no adverstising.

Whether your support is moral, financial, or both, thank you from the bottom of our hearts!

Bruno Dubuc, Patrick Robert, Denis Paquet, and Al Daigen




Tuesday, 12 June 2018
We Are Blind to Many of the Reasons for Our Conscious Choices

In a study that they conducted in 2005, entitled “Failure to detect mismatches between intention and outcome in a simple decision task”, Lars Hall and Peter Johansson uncovered a spectacular phenomenon. In this experiment, the researchers showed their subjects pairs of cards with pictures of two different people’s faces and asked their subjects to pick whichever of the two people they found more attractive. Once a subject had made this choice, the experimenter took back the cards and then, using a little sleight of hand, gave the subject back the card that he or she had not chosen and asked what it was about the person pictured that made them more attractive. Over 80% of the subjects failed to notice that they had been given the wrong card and actually provided the kind of verbal explanation requested—that it was the expressiveness of the person’s eyes or the overall harmoniousness of their features, or what have you. (more…)

From Thought to Language | No comments


Tuesday, 29 May 2018
What Chaos Physics Tells Us About the Dynamic Brain

Once upon a time, not that long ago in the history of neuroscience, the chaotic aspect of all of the brain’s neuronal oscillations was regarded as mere “background” noise. But that time is now past. The temporal dimension of brain activity, as expressed in cerebral rhythms, and the associated synchronization of neural activity, is now central to research in such complex areas as sleep and consciousness. Much of our current understanding of how the dynamic activity of the human brain can be chaotic and yet meaningful is owed to the pioneering research of Walter J. Freeman. (more…)

From the Simple to the Complex | No comments


Tuesday, 15 May 2018
Memory Engrams: The Physical Traces of Memories in Your Brain

In 1923, German biologist Richard Semon proposed the engram theory of memory. According to this theory, when a person experiences something, a set of selected stimuli from this experience activates entire populations of neurons in that person’s brain, thus inducing lasting chemical and physical changes in their connections. These changes are known as the engram. Each of the assemblies of neurons thus selected thereby contributes to the storage of the memory.

As we shall see in a moment, this was a visionary concept, but Semon’s theory was almost completely ignored until the 1970s, when an article by Daniel Schacter, James Eich, and Endel Tulving brought it back into the scientific discussion. (more…)

Memory and the Brain | No comments


Tuesday, 1 May 2018
Limitations of Brain Mapping

With the use of tracers, dyes and modern brain-imaging technology, it is now possible to produce maps of the human brain. But why would we want to do so? Simply because our cognitive functions emerge from interactions among numerous parts of the brain, in many cases physically quite distant from one another. If we can map the neural highways that form the various networks in our brains, or better still, understand which are the preferred highways for use in particular situations, we can learn a lot about how we go about talking, thinking and behaving.

But because the brain is so complex, brain mapping involves many problems and is subject to some major limitations. In this post I will discuss just two of these problems and a few limitations inherent in efforts to map the “connectome”—to prepare a map of all the nerve bundles connecting the neurons to one another in a given brain. (more…)

From the Simple to the Complex | No comments


Sunday, 25 March 2018
The Many Events Without Which We Wouldn’t Be Here To Talk About Them

In the course of evolution, there have been many times when the future existence of my brain as I write these lines and yours as you read them has hung by the slenderest thread. Without the events, many of them quite unlikely, that occurred at these times, we would not be here today to speculate about their nature (or at least not in our current form). (more…)

From the Simple to the Complex | No comments