After providing all the funding for The Brain from Top to Bottom for over 10 years, the CIHR Institute of Neurosciences, Mental Health and Addiction informed us that because of budget cuts, they were going to be forced to stop sponsoring us as of March 31st, 2013.

We have approached a number of organizations, all of which have recognized the value of our work. But we have not managed to find the funding we need. We must therefore ask our readers for donations so that we can continue updating and adding new content to The Brain from Top to Bottom web site and blog.

Please, rest assured that we are doing our utmost to continue our mission of providing the general public with the best possible information about the brain and neuroscience in the original spirit of the Internet: the desire to share information free of charge and with no adverstising.

Whether your support is moral, financial, or both, thank you from the bottom of our hearts!

Bruno Dubuc, Patrick Robert, Denis Paquet, and Al Daigen




Tuesday, 28 September 2021
Two pioneers in research on neurogenesis and vision

Today I just want to draw your attention to two researchers who are senior citizens but still active and still inspiring: Fred Gage and Deric Bownds.

Fred Gage recently gave http://charlesvaseyandco.co.uk/?et_core_page_resource=et-core-unified-115-cached-inline-styles115 an interview on his scientific career, in which he told how he became a pioneer in research on neurogenesis—the development of new neurons in the brains of adult mammals. It’s always interesting to learn about the scientific career of post-haste someone who disproved an idea that was previously dogma. In Gage’s case, it was the idea that had emerged during the last decades of the 20th century that when humans are born, their brains contain as many neurons as they will ever have and will only continue to lose them as their lives go on.

Although Gage disproved this bit of dogma, controversy remains as to which specific parts of the human brain neurogenesis can occur in, and up to what age. But one thing is certain: the two factors that Gage identified as greatly favouring neurogenesis in the brains of rodents — exercise and a rich, stimulating environment — are still two of the most beneficial things for the brain as a whole.

* * *

Regarding Deric Bownds, I just want to mark the 15th anniversary of his blog, can you buy prednisone online Deric’s MindBlog. Now retired, Bownds glamorously did research on the molecular mechanisms of vision, in particular on the photoreceptor cells in the retina that convert light energy into neural activity. Every day in his blog, he briefly summarizes a recent study in cognitive neuroscience and places it in the context of current debates in this vast field of research. His posts are so timely that I always provide links to his five most recent ones in the left-hand margin of the blog you’re reading now. In some of his posts, Bownds just summarizes scientific articles that have caught his attention, while in others he takes a deeper dive, but in any case, he remains a steady source of inspiration for me and hence for this blog.

From the Simple to the Complex | Comments Closed


If you have a comment, please e-mail it to me, and I will post it here.