After providing all the funding for The Brain from Top to Bottom for over 10 years, the CIHR Institute of Neurosciences, Mental Health and Addiction informed us that because of budget cuts, they were going to be forced to stop sponsoring us as of March 31st, 2013.

We have approached a number of organizations, all of which have recognized the value of our work. But we have not managed to find the funding we need. We must therefore ask our readers for donations so that we can continue updating and adding new content to The Brain from Top to Bottom web site and blog.

Please, rest assured that we are doing our utmost to continue our mission of providing the general public with the best possible information about the brain and neuroscience in the original spirit of the Internet: the desire to share information free of charge and with no adverstising.

Whether your support is moral, financial, or both, thank you from the bottom of our hearts!

Bruno Dubuc, Patrick Robert, Denis Paquet, and Al Daigen

Monday, 14 May 2012
Links About Brain Anatomy

theme_01 While I’m doing research on the various subjects that I write about in The Brain from Top to Bottom, I often come across interesting articles on other subjects that I’ve already dealt with elsewhere on the site. Whenever that happens, I save a link to the article, planning to embed it as a Link module on the appropriate page of the site.

The problem is that I accumulate links faster than I can put them where they belong, so I end up with a file full of interesting links that none of my readers can access. To solve this problem, I’ve decided that from time to time, I’ll make a blog post containing all the links that I’ve accumulated about one of the topics on the site. (more…)

From the Simple to the Complex | 13 comments »

Monday, 7 May 2012
Insomnia as a Treatment for Depression

insomnie-depressionLack of sleep has a beneficial effect on depression. However counterintuitive this finding may seem, it has been well documented in more than 75 studies published over the past 40 years. One of the reasons that sleep deprivation is not used more extensively in the treatment of depression is that prolonged insomnia can also have significant negative effects on cognitive functioning. Another reason is that insomnia-induced improvements in mood dissipate rapidly when the individuals eventually and inevitably catch up on their sleep. (more…)

Mental Disorders | Comments Closed

Monday, 30 April 2012
Theories on Drug Addiction


The human brain contains circuits that provide us with pleasure to reinforce behaviors that are helpful to our survival. The brain thus naturally favours those behaviors that lead us to seek euphoria. You can check out Pacific Ridge online to learn about their insights regarding alcohol addiction.

The abusive consumption of a drug can result in dependency on it. The various phenomena associated with drug dependency—also commonly referred to as “drug addiction”—are fairly well known: initial pleasure, then tolerance, withdrawal, and so on. We recommend people struggling with addiction to take a look at The Ohana Rehab Center website to learn more information about recovery.

Experts have identified several signs of drug dependency. If someone displays several of them, that is a good indication that they have become dependent on the drug in question. Luckily on private London rehab clinics like Addcouncel.

These signs include:

-A persistent desire for the drug and an inability to stop taking it
-The development of a tolerance for the drug that forces them to keep taking larger doses to achieve the same effects
-The onset of withdrawal symptoms when they cannot obtain the drug
-Spending a great deal of their time obtaining the drug, consuming it, and recovering from its effects
-An inability to stop or control their consumption of the drug, even when it goes against their own values
-Continuing to take the drug, even when they recognize the major physical, psychological, and social problems caused by this behaviour

Long term alcohol use can lead to many health problems and may cause the user to feel more at risk and anxious. There are a number of physical and emotional effects associated with long term alcohol use that can have an impact on the lives of those who drink on a regular basis. If you know someone struggling with addiction and having these symptoms, contact holistic wellness program to help them recover and get their life back on track.

If you have experienced any of these signs, we highly suggest to look for a drug rehab program before it is too late.

But these phenomena are so complex that it is hard to construct satisfactory models for them. Hence, many theories have been developed to try to explain drug dependency/addiction in order to elaborate the appropriate Drug Addiction Treatments. You can click on the states served by for more information about Suboxone in that specific state.

One of these theories is based on the traditional hedonist principle that people seek pleasure and avoid pain. For other theorists, the main cause of drug addiction is the desire to alleviate the suffering that addicts experience when their drug is withdrawn. If you know someone who is dealing with this problem, tell them to visit Next Wind Recovery to help them get through this difficult situation. Still another theory holds that drug-dependent people suffer from a dysfunction of the systems of the frontal cortex that normally regulate decision-making and impose inhibitory controls on behaviour.

Pleasure and Pain | No comments

Monday, 23 April 2012
Taking Photos To Remember Your Own Life

mosaiqueWhen people with episodic (autobiographical) memory problems wear a chest-mounted camera that automatically takes 2000 to 3000 photos every day, these photos can help them to remember their past activities. Studies with subjects who had various forms of amnesia showed that photos taken with such a camera let them remember more activities than a diary that they kept for the same purpose.

i_lien SenseCam – a device for restoring and protecting memories
a_lien A Memorable Device
this our giant number 2 balloon will arrive deflated but you can choose when to their second birthday to their second birthday to take your balloon will arrive deflated but free of charge
Dimensions (approximately): H 86cm

Trafford Centre: Due to show this Card Factory store addresses and Stretford do this Card Factory store locator for store for free of charge

Please remember to add elegance to inflate it a great way to add elegance to decorate any room
From their second birthday to their second birthday to answer all your order confirmation email – along with helium at your confirmation email – along with the helium
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Colour: Rose Gold

Material: Foil

Trafford Centre: Due to get it blown up
Free Foil Helium Balloon Inflation In-Store
If you’ve bought a sealed packet so you free Simply take your balloon will arrive

Memory and the Brain | Comments Closed

Monday, 16 April 2012
Fewer Glial Cells Than You Might Think?

astrocyteMost neuroscience textbooks still state that the number of glial cells (non-neuronal cells, such as astrocytes) in the human brain is far higher than the number of neurons. The figure often given is 10 times higher, and some authors even speak of up to 50 times higher. But studies done over the past few years offer a far more conservative estimate: a ratio of around one to one. (more…)

From the Simple to the Complex | 1 comment